ClearNote Health Raises $52 Million Series D to Advance AI-Powered Early Cancer Detection
San Diego-based precision diagnostics company ClearNote Health has secured $52 million in Series D funding to accelerate commercialization of its noninvasive cancer detection technologies and expand global access to early cancer screening solutions. The round was led by founding investor Mattias Westman alongside a major global long-only active investment manager, with participation from former Citigroup CEO Sandy Weill, ClearNote Health co-founder Dr. Stephen Quake, a large Seattle-based family office, and additional institutional investors. Founded around breakthrough research from Stanford University, ClearNote Health develops advanced epigenomic diagnostics capable of detecting difficult-to-diagnose cancers through blood-based testing. The company’s proprietary Virtuoso™ epigenomics platform combines artificial intelligence, genomics, and bioinformatics to identify active biological signals associated with cancer development. ClearNote Health’s Avantect® platform focuses initially on pancreatic and ovarian cancer detection - two cancers where early diagnosis dramatically improves survival outcomes. The company says its blood-based screening systems may enable detection earlier than conventional diagnostic methods in high-risk patient populations. The startup also announced the appointment of clinical diagnostics veteran Kevin Keegan as President and COO. Keegan previously held senior leadership roles at Illumina, BD, and Hologic, where he helped scale major oncology diagnostic platforms globally. According to the company, the fresh capital will support commercial expansion, operational scaling, product development, clinical study execution, and broader deployment of its early cancer detection portfolio. ClearNote Health’s multi-cancer detection platform was recently selected as one of only two blood-based technologies for the US National Cancer Institute’s Vanguard Study. The funding reflects accelerating investor interest in AI-powered precision medicine, liquid biopsy technologies, genomics infrastructure, and preventive healthcare systems capable of improving early cancer detection at population scale.
Pivot Raises $40 Million Series B to Replace Legacy Procurement Software With an AI Operating System
Paris and New York-based enterprise AI startup Pivot has secured $40 million in an oversubscribed Series B funding round to modernize corporate procurement infrastructure with agentic AI. The round was co-led by Forestay Capital and Notion Capital, with participation from Greyhound Capital, Hedosophia, Visionaries Club, Emblem, and multiple senior procurement industry operators including former SAP Ariba executives and EcoVadis founder Pierre-François Thaler. Founded in 2023 by Marc-Antoine Lacroix, Romain Libeau, and Estelle Giuly, Pivot is building an AI-native procurement operating system that automates sourcing, approvals, purchasing, invoicing, payments, vendor workflows, expense management, and reporting. The platform integrates deeply with ERP and finance systems to provide enterprises with real-time visibility into committed spending before invoices are finalized. Unlike traditional procurement software providers such as SAP Ariba and Coupa, Pivot positions itself as a fully AI-native infrastructure layer rather than a legacy workflow tool retrofitted with automation. The company says its architecture enables AI agents to operate directly inside procurement workflows with full contextual financial visibility instead of relying on fragmented spreadsheets, email chains, and disconnected systems. Pivot already counts DoorDash, Lemonade, and Flix among its enterprise customers and reportedly processes billions of dollars in invoices annually across more than 25 countries. The fresh capital will support expansion of its agentic AI capabilities, deeper ERP integrations, enterprise scaling, and international hiring across EMEA and the United States. The funding reflects accelerating investor interest in enterprise AI infrastructure modernizing back-office operations including procurement, finance operations, compliance, and enterprise workflow orchestration. Procurement is increasingly emerging as one of the largest untapped categories for agentic AI deployment globally.
OpenRouter Raises $113 Million Series B to Become the Universal Routing Layer for AI Models
AI infrastructure startup OpenRouter has secured $113 million in Series B funding to accelerate expansion of its multi-model AI routing and inference platform powering developers and enterprises across the generative AI ecosystem. The round was led by Andreessen Horowitz (a16z) and Menlo Ventures, with participation from Sequoia Capital, Lightspeed Venture Partners, SV Angel, and strategic AI infrastructure investors. Founded by Alex Atallah and the OpenRouter team, the company operates a universal API layer that allows developers to access and dynamically route requests across multiple leading AI models including OpenAI, Anthropic, Google Gemini, Mistral, Meta Llama, Cohere, and open-source models through a single infrastructure endpoint. OpenRouter has rapidly emerged as critical middleware infrastructure within the AI ecosystem by helping companies optimize cost, latency, reliability, availability, and model selection across rapidly evolving AI providers. The platform increasingly serves as an orchestration layer for enterprises building production-grade generative AI systems and agentic AI applications. The company stated that the fresh capital will support scaling of global inference infrastructure, enterprise security features, observability tooling, routing optimization systems, and advanced AI orchestration capabilities. OpenRouter is also investing heavily in agent infrastructure, model interoperability, and intelligent workload balancing across heterogeneous AI systems. The funding highlights surging investor interest in AI middleware, model orchestration, inference optimization, and developer infrastructure as enterprises increasingly adopt multi-model AI strategies instead of relying on a single foundation model provider.
Thea Energy Raises $100 Million Series B to Build Scalable Fusion Power Plants for the AI Era
New Jersey-based fusion energy startup Thea Energy has secured $100 million in Series B funding to accelerate development of its stellarator-based fusion energy systems designed to deliver scalable, carbon-free electricity. The round was led by Prelude Ventures and Lowercarbon Capital, with participation from Anglo American, Hitachi Ventures, Mercuria, Chevron Technology Ventures, Alumni Ventures, and several strategic industrial investors. Founded by Brian Berzin, Thea Energy is developing advanced stellarator fusion reactors that use powerful magnetic confinement systems to generate fusion energy through superheated plasma reactions. Unlike traditional tokamak fusion designs, stellarators are engineered for continuous steady-state operation with potentially greater long-term stability and efficiency. The company stated that the fresh capital will support construction of its integrated fusion engineering systems, plasma control technologies, superconducting magnet development, and expansion of its manufacturing and simulation capabilities. Thea Energy is also scaling partnerships with industrial and energy infrastructure players to accelerate commercialization pathways for fusion-generated electricity. Investors are increasingly viewing fusion as a strategic long-term energy solution capable of powering the rapidly growing computational demand driven by artificial intelligence, hyperscale data centers, advanced manufacturing, and electrification infrastructure. The sector has seen significant capital inflows as governments and corporations race to secure next-generation clean energy technologies. Thea Energy joins a growing wave of fusion startups attempting to commercialize practical fusion power through breakthroughs in superconductors, plasma physics, AI-assisted simulation systems, and advanced materials engineering.
Didit Raises €2 Million Seed Funding to Build Privacy-First Digital Identity Infrastructure
Spanish identity verification startup Didit has secured €2 million in seed funding to accelerate development of its privacy-focused digital identity and KYC infrastructure platform. The round was led by JME Ventures, with participation from Lanai Ventures, OSS Capital, and several strategic angel investors focused on cybersecurity, fintech, and digital trust technologies. Founded by Sergio García and Alberto Rodríguez, Didit develops decentralized identity verification systems that allow users to securely prove identity online without repeatedly sharing sensitive personal data across platforms. The company combines biometric verification, reusable digital credentials, AI-powered fraud detection, and blockchain-based trust infrastructure to streamline onboarding and compliance workflows. The startup says its platform is designed to help fintechs, crypto platforms, marketplaces, gaming companies, and enterprise platforms comply with increasingly strict KYC and AML regulations while improving user privacy and reducing onboarding friction. Didit positions itself as a next-generation digital identity layer aligned with Europe’s evolving eIDAS 2.0 and digital wallet frameworks. According to the company, the fresh capital will support engineering expansion, AI fraud prevention systems, product development, and broader European rollout of its reusable identity infrastructure. The startup is increasingly targeting sectors where secure identity verification, trust, and regulatory compliance are becoming mission-critical digital infrastructure components. The funding highlights rising investor interest in decentralized identity systems, AI-powered trust infrastructure, privacy-preserving authentication, and digital compliance technologies as online fraud and regulatory requirements continue to grow globally.
Fairdeal.Market Raises $15 Million Series A to Scale India’s Kirana Quick Commerce Infrastructure
Gurugram-based B2B quick commerce startup Fairdeal.Market has secured $15 million in Series A funding to accelerate expansion of its kirana-focused inventory replenishment network across India. The round was led by Bertelsmann India Investments (BII), with participation from existing investors WaterBridge Ventures and Incubate Fund Asia. Founded by Prateek Bansal and Yash Bansal, Fairdeal.Market operates a dark-store-led supply chain platform enabling kirana retailers to replenish inventory within 60 minutes. The startup currently delivers more than 1,000 SKUs across Delhi NCR and has scaled to over 20,000 active retailers within the past six months. The company stated that the fresh capital will be used to expand dark-store operations across dense urban clusters, strengthen technology and data infrastructure, deepen retailer engagement, and scale last-mile delivery capabilities. Fairdeal aims to grow its retailer network to more than 100,000 retailers during the current financial year. Fairdeal is positioning itself as a next-generation procurement infrastructure layer for India’s massive kirana ecosystem, where inventory sourcing has traditionally relied on fragmented offline wholesale markets and inefficient distributor networks. The startup says its high-frequency replenishment model helps improve inventory turns, shelf efficiency, and working capital utilization for small retailers. Beyond logistics, the company is also building a real-time retail intelligence platform that provides FMCG and consumer brands visibility into demand trends, inventory movement, and retailer purchasing behavior across local markets. Investors are increasingly viewing B2B quick commerce as a major opportunity within India’s digitizing retail infrastructure ecosystem.